Deconvoluted activity fitness scores of the D-amino acid oxidase (DAOX) from the yeast Rhodoturula gracilis investigated through enzyme proximity sequencing (EP-Seq).
Activity score was normalized over the expression score for each variant DAOx with expression score higher than the one of nonsense mutants.
See the manuscript describing these data here
Raw data available here
Heatmap of the expression and activity scores available here
Instructions
- Move the mouse over cells to reveal additional information.
- Explore the activity score values using the sliders below the plots.
- Structural information of the DAOx enzyme (PDB:1c0p) is displayed above the heatmaps.
- Select positions corresponding to specific structural elements from the drop down menu below the plots
- Change the range of sites showed by by brushing the zoom bar and dragging the brush.
- Clear the zoom bar by double clicking it.